Nursing
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Practice Alerts & Guidelines
Blood Component Administration by LPNs
Course Outline for Training LPNs in
Blood Component Administration
Approved by the New York State Department of Health and the
New York State Education Department
PURPOSE
The purpose of this course outline is to provide a guide for
organizations in developing and implementing a standardized
curriculum for the training of LPNs in their role in blood
component administration.
PREREQUISITE
Completion of an LPN IV therapy training program as required
by the New York State Board for Nursing.
COURSE OBJECTIVES
Upon completion of training, the LPN will be able to:
- List common indications for therapeutic blood component
administration.
- List the patient data to be obtained prior to blood component
administration.
- Identify the steps for preparation of supplies and equipment
for blood component administration.
- Describe the patient identification process to be verified at
the patient’s side with the RN prior to blood component
administration.
- Demonstrate clinical competency in safe blood component
administration.
- Identify the actions to take in the event of a transfusion
reaction.
- Document blood component administration according to
institutional policies and procedures.
ESSENTIAL COURSE CONTENT
- Applicable Requirements and Guidance
- Guideline: The Differentiated Scope of Practice of Licensed
Practical Nurses (LPNs) and Registered Professional Nurses
(RNs)
- Guideline: The Practice of IV Therapy by Licensed Practical
Nurses in Acute Care Settings
- Education Law, Article 139, Section 6902.2
- Regent’s Rules, Sections 29.1(b)(9), 29.1(b)(10), and
29.2
- DOH regulations, Subpart 58-2
- DOH Guidelines for Monitoring Transfusion Recipients
- Institutional policies and procedures pertaining to blood
administration, including the roles of LPNs and RNs and infection
control practices
- Types of Blood Components
- Content, how they are prepared, physiologic
action/therapeutic effects
- Packed red blood cells, including autologous and directed
donations
- Platelets, including whole blood-derived concentrates and
apheresis platelets
- Fresh frozen plasma and other types of plasma
- Other components used at the facility (e.g., cryoprecipitate,
granulocytes)
- Components that undergo special processing, such as
irradiated, leukoreduced, CMV-safe, sickle hemoglobin negative
components, and HLA-matched or crossmatched platelets
- Indications for Blood Component Administration
- Packed red blood cells – including chronic anemias,
acute blood loss due to trauma or surgery
- Platelets – including thrombocytopenia due to disease
or chemotherapy, platelet dysfunction, platelet consumption, with
bleeding; prior to invasive procedure or prophylactic; not
indicated in ITP/TTP absent life-threatening bleeding
- Fresh frozen plasma and other types of plasma –
coagulation factor deficits other than Factor VIII; not indicated
for volume replacement
- Blood Groups and Compatibility
- ABO groups (O, A, B, and AB)
- Rh (Rh-positive, Rh-negative; influence of latter on
perinatal care)
- Other blood groups (blood may be labeled negative for other
antigens)
- ABO compatibility of cellular components
- ABO compatibility of plasma components
- Information Needed Prior to Blood Administration
- Prescription by authorized provider
- Order(s) for posttransfusion laboratory tests to assess
efficacy
- Review pertinent pretransfusion and historical laboratory
values (blood group & Rh) and patient status
(hemoglobin/hematocrit for red blood cells, platelet count for
platelets, PT/APTT for FFP; presence/absence of bleeding, planned
invasive procedure, if any)
- Vital signs, baseline and historical
- Patient history pertinent to transfusion, prior transfusions
(blood group & Rh ) and any reactions; prior
transfusion-related pregnancy complications, such as infant with
hemolytic disease of the newborn or bleeding at birth
- Administration Techniques, According to Institutional
Policies and Procedures
To include:
- Confirmation of prescribed order with RN or physician*
- Confirmation of current patient consent
- Verification of blood group & Rh and transfusion
history
- Patient preparation, including patient education
- Obtaining pre-administration baseline patient data, including
vital signs
- Preparation of equipment and supplies, in accordance with
infection control standards
- Assessment of patency and size of peripheral venous access by
RN
- Procedures for obtaining blood components
- Administration of pre-transfusion medications if
indicated
- Patient identification process, including comparison of the
blood component label with other information and identifying
recipient and blood component at the patient’s side, with
RN or physician*
- Infusion rates and duration
- Documentation of patient data during blood component
administration
- Reporting changes in patient data/vital signs to RN or
physician*, if outside established limits, following comparison
with patient baseline and established parameters
- Required documentation
- Disposition of supplies and equipment
- Reporting patient data at the time of transfusion completion
to RN or physician*
- Transfusion Reactions
- Immediate reactions, including acute hemolytic transfusion
reactions, bacterial contamination, transfusion-related acute
lung injury (TRALI), febrile nonhemolytic transfusion reactions,
allergic reactions, urticarial reactions, and volume overload
- Signs and symptoms
- LPN responsibilities, if signs/symptoms are outside of
established parameters (discontinue administration of blood and
alert RN and/or physician*)
- Transfusion reaction protocol (including clerical check,
blood and urine specimens, and retention of the component bag[s])
and LPN role
- Interventions/therapy, as ordered by a physician*
- Delayed reactions, including delayed hemolytic transfusion
reactions, posttransfusion purpura
- Signs and symptoms
- LPN responsibilities (alert RN and/or physician*)
- Interventions/therapy, as ordered by a physician*
*Physician, or other person authorized by law
to order transfusions
CLINICAL EXPERIENCE
Following completion of didactic instruction and supervised
clinical experiences, each LPN must undergo clinical competency
validation. This process includes direct observation of
successful blood component administration tasks for each of the
types of components for which the LPN will be authorized to
administer, using the particular equipment employed at the
institution. Until such competency is established and documented,
LPNs may administer blood components only under direct,
line-of-sight supervision of an RN.
An ongoing competency maintenance program, at a minimum,
should include annual clinical competency validation of blood
product administration, as defined by institutional policies and
procedures.
MODIFICATIONS
When an institution modifies the LPN role and responsibilities
for administering blood components, RNs must complete an
appropriate educational program to ensure that blood
administration tasks are delegated to LPNs according to the
current standards of practice and institutional policies and
procedures.
When blood administration procedures are modified, LPNs
performing blood administration tasks must undergo appropriate,
documented training in the modified procedures, in accordance
with revised standard operating procedures and a revised
curriculum.
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